Hydrochloric Acid → Phosphonic acid, [2-nitro-5-[2-nitro-4-(trifluoromethyl)phenoxy]phenyl]-

HRID 904797Notes

Reaction equation

HRID 904797 reaction equation
C([O:3][P:4]([C:9]1[CH:14]=[C:13]([O:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][C:17]=2[N+:26]([O-:28])=[O:27])[CH:12]=[CH:11][C:10]=1[N+:29]([O-:31])=[O:30])(=[O:8])[O:5]CC)C.Cl>C(O)C>[N+:29]([C:10]1[CH:11]=[CH:12][C:13]([O:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:23])([F:24])[F:25])=[CH:18][C:17]=2[N+:26]([O-:28])=[O:27])=[CH:14][C:9]=1[P:4](=[O:3])([OH:5])[OH:8])([O-:31])=[O:30]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54178647HCID 54178647, compound

Product 1

HCID 20476548Phosphonic acid, [2-nitro-5-[2-nitro-4-(trifluoromethyl)phenoxy]phenyl]-

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1.85 g of the 2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester obtained in Example 1, in 20 ml of ethanol, and 40 ml of 20% hydrochloric acid, is refluxed for 24 hours and then evaporated to dryness, affording as residue the monohydrate of the corresponding free phosphonic acid in the form of yellowish brown crystals in quantitative yield. Melting point: 175°-180° C.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-8634db61959f46188592cc0ee9a16c41
Source dataset
uspto-grants-1983_12
Patent number
US04420436

Reaction notes

Loading…