Acetic Anhydride → HCID 9859076, compound

HRID 904821Notes

Reaction equation

HRID 904821 reaction equation
[N:1](=[C:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4]1)O.[C:13](OC(=O)C)(=[O:15])[CH3:14].[O:20]1CCCC1>[Pd]>[C:13]([NH:1][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:20])(=[O:15])[CH3:14]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 8028TetrahydrofuranHCID 71437055HCID 71437055, compound

Product 1

HCID 9859076HCID 9859076, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A slurry of 2-oximino-3,4-dihydronaphthalen-[1(2H)-one (8.75 gm, 0.05 m) acetic anhydride (25 ml), tetrahydrofuran (150 ml) and Pd/C (10%, 500 mg) was hydrogenated on a Parr apparatus for 3 hours. The catalyst was removed by filtration through diatomaceous earth. The organic solvents were evaporated under reduced pressure (20 mm) to yield the product as an oil, which was used in the next step without further purification.

Workup

  1. customThe catalyst was removed by filtration through diatomaceous earth
  2. customThe organic solvents were evaporated under reduced pressure (20 mm)

Sources & evidence

ORD record
ord-74327dc6bb1e4c6e844b4c077bc9bd0a
Source dataset
uspto-grants-1983_12
Patent number
US04420480

Reaction notes

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