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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 904834Generated: October 30, 2026

Sodium Hydroxide → HCID 178508177, compound

https://huagongshe.com/reaction/904834

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 53901979HCID 53901979—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
ProductHCID 178508177HCID 178508177—

Reaction Steps

1-Isopropylsulfonyl-2-amino-6-(α-chloromethylenebenzyl)benzimidazole is reacted with sodium hydroxide in acetone and water by the method of Example 43 to give 2-amino-6-(α-chloromethylenebenzyl)benzimidazole. The latter compound is reacted with phenylsulfonyl chloride and sodium hydroxide in dichloromethane to give 1-phenylsulfonyl-2-amino-6-(α-chloromethylenebenzyl)benzimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04420479
Source datasetuspto-grants-1983_12
ORD IDord-d1ea789a3c3a47b4b2a9b0ac95e685e6
Source noteuspto-grants-1983_12