反应详情

A mixture of 2.21 g. of 2-amino-4-chloro-5-sulfamylaniline (VI), 50 ml. of glacial acetic acid, and 1.05 g. of benzaldehyde was refluxed for 16 hours and then decanted into water. The precipitate was collected by filtration, dissolved in ethanol, treated with Darco, filtered through filter paper and then through Celite. Concentration in vacuo provided a solid which was dissolved in ethanol, filtered, and forced out with water. Treatment of this beige solid with boiling acetronitrile provided an off-white solid mp 314°-316°.

1. additionA mixture of 2.21 g
2. customdecanted into water
3. filtrationThe precipitate was collected by filtration
4. dissolutiondissolved in ethanol
5. additiontreated with Darco
6. filtrationfiltered
7. filtrationthrough filter paper
8. concentrationConcentration in vacuo
9. customprovided a solid which
10. filtrationfiltered