N,N-Dimethylethylenediamine → 3-Pyridinecarbonitrile, 2-[[2-(dimethylamino)ethyl]amino]-4,6-dimethyl-

Participants

Role	Name	HCID	Charge
Reactant	N,N-Dimethylethylenediamine	HCID 66053	—
Reactant	2-Chloro-4,6-dimethyl-3-pyridinecarbonitrile	HCID 223261	—
Product	3-Pyridinecarbonitrile, 2-[[2-(dimethylamino)ethyl]amino]-4,6-dimethyl-	HCID 3411877	—

Reaction Conditions

Temperature	105 °C

Reaction Steps

A mixture of 2-chloro-3-cyano-4,6-dimethylpyridine (10.0 g, 60 mmol) and N,N-dimethyl-1,2-diaminoethane (10.6 g, 120 mmol) is heated at 105° C. for 20 hours. Added benzene, evaporated to dryness, dissolved residue in water, made basic with sodium carbonate and extract product into methylene chloride, dried and evaporated to give 13.4 g of oily title A product.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04420615
Source dataset	uspto-grants-1983_12
ORD ID	ord-ee2be81bdfd74efc91c78ad5d195ad40
Source note	uspto-grants-1983_12