反应详情

温度

105 °C

A mixture of 2-chloro-3-cyano-4,6-dimethylpyridine (10.0 g, 60 mmol) and N,N-dimethyl-1,2-diaminoethane (10.6 g, 120 mmol) is heated at 105° C. for 20 hours. Added benzene, evaporated to dryness, dissolved residue in water, made basic with sodium carbonate and extract product into methylene chloride, dried and evaporated to give 13.4 g of oily title A product.

1. customAdded benzene, evaporated to dryness
2. dissolutiondissolved residue in water
3. extractionextract product into methylene chloride
4. customdried
5. customevaporated
6. customto give 13.4 g of oily title A product