Dimethyl Sulfate → HCID 13565196, compound

HRID 904907Notes

Reaction equation

[CH2:1]([N:5]([CH:7]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:11]=1)[C:8]#[N:9])[CH3:6])[CH:2]([CH3:4])[CH3:3].[S:23]([O:28]C)([O:26][CH3:27])(=[O:25])=[O:24]>>[CH3:27][O:26][S:23]([O-:28])(=[O:25])=[O:24].[C:8]([CH:7]([N+:5]([CH2:1][CH:2]([CH3:4])[CH3:3])([CH3:27])[CH3:6])[C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:11]=1)#[N:9]

Participants

Reactant 2

HCID 6497Dimethyl Sulfate

HCID 13565195HCID 13565195, compound

Product 1

HCID 13565196HCID 13565196, compound

Conditions

Temperature: 100 °C

Procedure

A mixture of α-(N-isobutyl-N-methylamino)-3-phenoxybenzeneacetonitrile (7.35 g) and dimethyl sulfate (3.15 g) was stirred at a temperature of 100° C. for a period of 4 hours to give N-(α-cyano-3-phenoxybenzyl)-N-isobutyl-N,N-dimethylammonium methyl sulfate. Proton nuclear magnetic resonance spectrum (d6 -acetone; δ in ppm): 1.18 (6H, d of d); 3.45 (3H, s); 3.53 (3H, s); 6.84 (1H, s); 7.0-7.7 (9H, m).

Sources & evidence

ORD record: ord-715237fe92c14550bfdb49658c1cc3b1
Source dataset: uspto-grants-1983_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04420614

Reaction notes

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