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Six grams of powdered potassium hydroxide was dissolved in a mixture of 21.8 g of 2-(p-prenylphenyl)propionic acid in 125 ml of hexamethylphosphoric triamide and 125 ml of ethyl alcohol with stirring at room temperature. To the solution was added 27.4 g of n-butyl bromide and the mixture was stirred at room temperature for 24 hours. The mixture was poured into 500 ml of water and extracted with n-hexane. The extract was washed with 2 N hydrochloric acid, water, 5% aqueous sodium hydroxide and water successively, and dried over anhydrous magnesium sulfate. The solvent was evaporated to give 17.3 g of n-butyl 2-(p-prenylphenyl)propionate. b.p. 131°-133° C./0.15 mmHg, IR νmaxneat ; 1730 cm-1.

1. stirringthe mixture was stirred at room temperature for 24 hours
2. extractionextracted with n-hexane
3. washThe extract was washed with 2 N hydrochloric acid, water, 5% aqueous sodium hydroxide and water successively
4. dry with materialdried over anhydrous magnesium sulfate
5. customThe solvent was evaporated