Dabco → HCID 13245356, compound

HRID 904989Notes

Reaction equation

HRID 904989 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[S:11]([N:14]=[C:15]=[O:16])(=[O:13])=[O:12])=[O:4].[NH2:17][C:18]1[N:22]=[C:21]([O:23][CH3:24])[N:20]([CH3:25])[N:19]=1.C1N2CCN(CC2)C1>C(Cl)Cl>[CH3:24][O:23][C:21]1[N:20]([CH3:25])[N:19]=[C:18]([NH:17][C:15]([NH:14][S:11]([C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:3]([O:2][CH3:1])=[O:4])(=[O:12])=[O:13])=[O:16])[N:22]=1

Participants

5

Reactant 3

HCID 9237DabcoHCID 156281Benzoic acid, 2-(isocyanatosulfonyl)-, methyl esterHCID 129576645-Methoxy-1-methyl-1H-1,2,4-triazol-3-amine

Product 1

HCID 13245356HCID 13245356, compoundYield 72.9%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 2-(methoxycarbonyl)benzenesulfonylisocyanate (80%, 1.41 g, 4.7 mmol) in methylene chloride (10 ml) at room temperature under nitrogen was added 3-amino-5-methoxy-1-methyl-1H-1,2,4-triazole (0.50 g, 3.9 mmol). DABCO (catalytic amount) was added, and the reaction mixture was stirred for 3 days. Isolation of the product by filtration and washing with methylene chloride gave 1.05 g of a white powder, m.p. 177°-180°.

Workup

  1. filtrationIsolation of the product by filtration
  2. washwashing with methylene chloride

Sources & evidence

ORD record
ord-ebf8d7fee8194f31a2f1a96c61fbe369
Source dataset
uspto-grants-1983_12
Patent number
US04421550

Reaction notes

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