Hydrochloric Acid → HCID 13200167, compound

Participants

Reaction Steps

The resulting 4-(benzoylmethyl)-1-(N-nitrosocyanomethylamino)piperazine was dissolved in 10 ml of methanol. In the solution was added 12 ml of 10% methanolic hydrochloric acid, and the mixture was reacted at 5° C. overnight. The reaction mixture was concentrated under reduced pressure, and the residue was recrystallized from methanol-ether to give 1.8 g (yield 81.8%) of 3-[4- (benzoylmethyl)piperazin-1-yl]sydnonimine dihydrochloride having a melting point of 182° to 184° C. (decomp.).

Provenance & Evidence