HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 54085372, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 54552195 | HCID 54552195 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 54085372 | HCID 54085372 | 96% |
Reaction Steps
A solution of ethyl 2-tert-butoxycarbonylamino-3-(3'methoxyphenyl)-4-fluoro-3-butenoate (218 mg) in ether (10 ml) saturated with dry HCl is left overnight by which time colorless needles crystallize. These are collected and dried to afford pure recemic ethyl 2-amino-3-(3'-methoxyphenyl)-4-fluoro-3-butenoate (150 mg): colorless needles, m.p. 141°-142°:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04421767 |
| Source dataset | uspto-grants-1983_12 |
| ORD ID | ord-d0fbd0457dd84d1aac261dd402d9f126 |
| Source note | uspto-grants-1983_12 |