Hydroxide → 4-(2-Fluoro-5-(tetrahydro-2H-pyran-4-YL)pyridin-3-YL)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine

HRID 90508Notes

Reaction equation

HRID 90508 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[O:1]1[CH2:2][CH2:3][C:4]([c:7]2[cH:8][c:9](-[c:14]3[n:15][c:16]([N:21]([CH2:22][c:23]4[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]4)[CH2:31][c:32]4[cH:33][cH:34][c:35]([O:38][CH3:39])[cH:36][cH:37]4)[n:17][c:18]([CH3:20])[n:19]3)[c:10]([F:13])[n:11][cH:12]2)=[CH:5][CH2:6]1.[OH-:45].[OH-:47].[Pd+2:46]>>[O:1]1[CH2:2][CH2:3][CH:4]([c:7]2[cH:8][c:9](-[c:14]3[n:15][c:16]([N:21]([CH2:22][c:23]4[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]4)[CH2:31][c:32]4[cH:33][cH:34][c:35]([O:38][CH3:39])[cH:36][cH:37]4)[n:17][c:18]([CH3:20])[n:19]3)[c:10]([F:13])[n:11][cH:12]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 8028TetrahydrofuranHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 66600402HCID 66600402, compound

Product 1

HCID 666000634-(2-Fluoro-5-(tetrahydro-2H-pyran-4-YL)pyridin-3-YL)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine

Sources & evidence

ORD record
ord-0bb52902a8d24aa1b34cf1d66eadb617
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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