HCID 14203475, compound → 83112-44-1

HRID 905178Notes

Reaction equation

HRID 905178 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 14203475HCID 14203475, compound

Product 1

HCID 1474284483112-44-1

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the prsence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen had been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

Workup

  1. customof hydrogen had been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-f58116059e5940ad8278e134a5d95d66
Source dataset
uspto-grants-1983_12
Patent number
US04423045

Reaction notes

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