Thiophenol → HCID 14320983, compound

HRID 905210Notes

Reaction equation

HRID 905210 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[C:9]1([SH:15])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:9]1([S:15][C:2]2[N:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 7969ThiophenolHCID 6066655-Bromo-2-chloropyrimidine

Product 1

HCID 14320983HCID 14320983, compound

Procedure

The title compound was prepared from 2-chloro-5-bromo-pyrimidine and thiophenol as described in Example 1; yield: 90% of a non-crystalline product which was pure enough for the successive oxidation. MS m/e: 267 (M, 100%). 1H NMR (CDCl3): δ7.4 (Ph), 8.50 (H-4, H-6).

Sources & evidence

ORD record
ord-4b855e48ad724771a974ea21fa1c8e96
Source dataset
uspto-grants-1983_12
Patent number
US04423047

Reaction notes

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