反应详情

A mixture of 5-chloropyrimidine-2-thione (3 mmol) and methylisocyanate (4 mmol) in dichloromethane (15 ml) was stirred at room temperature for 2 h, the solvent was then distilled off and the residue was crystallised from CHCl3 : Pet. ether; yield 85%, m.p. 115° C. 1H NMR (CDCl3) δ3.03 (Me), 8.62 (H-4, H-6).

1. distillationthe solvent was then distilled off
2. customthe residue was crystallised from CHCl3