HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 20475754, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | HCID 20475729 | HCID 20475729 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20475754 | HCID 20475754 | 88% |
Reaction Steps
The oxidation of 2-benzylthio-5-chloropyrimidine was carried out using one molar equivalent of 85% m-chloroperbenzoic acid in dichloromethane, initially at -10° C. and then at 0° C., as described in Example 40 above; yield 88%, m.p. 92° C. (iPrOH). 1H NMR (CDCl3) δ4.30 and 4.33 (CH2), 7.23 (Ph), 8.73 (H-4, H-6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04423047 |
| Source dataset | uspto-grants-1983_12 |
| ORD ID | ord-c92f9083ce0d490a876e6a7d259dd4d3 |
| Source note | uspto-grants-1983_12 |