1,2,4-Butanetriol → HCID 20476161, compound

Participants

Reaction Steps

Into a perfectly clean and dry flask were introduced 106.1 g (1 mol) of rectified 1,2,4-butanetriol and 1600 ml of anhydrous pyridine. While stirring, 507.4 g (3.12 mols) of di-n-propylacetyl chloride were added in 60 to 90 minutes care being taken to maintain the temperature below 30° C. The reaction medium was then stirred at room-temperature for 72 hours. The subsequent operations of purification were identical to those carried out in the foregoing Example 13.

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