HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 23071570, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 4-bromobutyrate | HCID 76300 | — |
| Reactant | 1-(4-Nitrophenyl)piperazine | HCID 80447 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 23071570 | HCID 23071570 | — |
Reaction Steps
1-(4-Nitrophenyl)piperazine and ethyl 4-bromobutanoate were allowed to undergo the reaction under heating in 1-methyl-2-pyrrolidone in the presence of potassium carbonate. The resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain ethyl 4-[4-(4-aminophenyl)-piperazin-1-yl]butanoate. F: 264.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012959B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-ca54b7f897414b9f8517b35d53652f42 |
| Source note | uspto-grants-2011_09 |