914389-14-3 → HCID 67404113, compound

Participants

Reaction Steps

To a suspension of N-{2-[2-[(3-fluorophenyl)imino]-4-(4-morpholin-4-ylphenyl)-1,3-thiazol-3(2H)-yl]ethyl}-N′-methylurea (455 mg) in chloroform (50 ml) was added 25% HBr/AcOH (0.32 g), and the mixture was stirred to dissolve for 30 minutes. The solvent was removed, and then thereto was added diethylether and a precipitate was filtered to give crystals (520 mg) of which a melting point was 191 to 193° C.

Provenance & Evidence