反应详情

[1-(2,2,2-Trifluoro-ethyl)-piperidin-3-yl]-carbamic acid tert-butyl ester (0.380 g, 1.3 mmol) was dissolved in 3 mL of dioxane. A 4 M solution of HCl in dioxane (3.3 mL, 13.3 mmol) was added and the resulting mixture was stirred overnight at RT before being evaporated to give racemic 1-(2,2,2-trifluoro-ethyl)-piperidin-3-ylamine hydrochloride.

1. custombefore being evaporated