反应详情

To a solution of 1-benzyl 4-tert-butyl piperidine-1,4-dicarboxylate in EtOAc (0.1 M), a catalytic amount of Pd/C (5%) was added and the atmosphere in the reaction vessel charged with H2 (1 atmosphere). The reaction mixture was stirred vigorously at RT for 8 h. The solution was filtered and the filtrate concentrated in vacuo to afford the title compound (76%); MS (ES+) m/z 186(M+H)+

1. additionthe atmosphere in the reaction vessel charged with H2 (1 atmosphere)
2. filtrationThe solution was filtered
3. concentrationthe filtrate concentrated in vacuo