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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906211Generated: October 26, 2026

2,5-Diazabicyclo(2.2.2)octane dihydrochloride → 4-(5-Isopropyl-2,5-diazabicyclo[2.2.2]octan-2-yl)aniline

https://huagongshe.com/reaction/906211

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Diazabicyclo(2.2.2)octane dihydrochlorideHCID 22924390—
Reactant4-((1S,4S)-5-Isopropyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-phenylamineHCID 57963911—
Product4-(5-Isopropyl-2,5-diazabicyclo[2.2.2]octan-2-yl)anilineHCID 57963921—

Reaction Steps

This compound is prepared according to the same procedure as described for Intermediate 7 using 2,5-diazabicyclo[2.2.2]octane dihydrochloride (J. Heterocycl. Chem, 1974, 11, 449-451).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012983B2
Source datasetuspto-grants-2011_09
ORD IDord-69d7951286944b21aaff80d3b4265701
Source noteuspto-grants-2011_09