5,8-Dibromo-(1,2,4)triazolo(1,5-a)pyrazine → HCID 57963930, compound

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Reaction Steps

To the solution obtained from step 2 is added 5,8-dibromo[1,2,4]triazolo[1,5-a]-pyrazine (1.6 g; 5.8 mmol) and triethylamine (3.4 mL). The resulting mixture was heated at reflux for 70 h, after which the reactor contents were cooled down and filtered to remove solids. The filter cake was washed with 2-MeTHF (2×5 mL) and the filtrate used as such in the next step.

Provenance & Evidence