Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 5,5-Dimethyl-2-methylsulphanyl-3,4,5,6-tetrahydropyrimidinium hydroiodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 5,5-Dimethyl-1,4,5,6-tetrahydro-pyrimidine-2-thiol | HCID 3866487 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5,5-Dimethyl-2-methylsulphanyl-3,4,5,6-tetrahydropyrimidinium hydroiodide | HCID 86600167 | — |
반응 단계
The reaction mixture comprising one equivalent of 5,5-dimethyl-3,4,5,6-tetrahydro(1H)pyrimidine-2-thione and 1.2 equivalents of iodomethane in methanol (10 ml/g of thio-urea) is heated under reflux for 5 hours. After cooling down, the methanol is evaporated off under reduced pressure in order to quantitatively produce the product. The precipitate can then be washed in acetone or petroleum ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08012985B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-74e08c4ab9b149f9950b4f135f462d6e |
| 출처 메모 | uspto-grants-2011_09 |