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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906349Generated: October 25, 2026

3-Fluoro-4-methoxyaniline → 1,1-Dimethylethyl 4-{[3-fluoro-4-(methyloxy)phenyl]amino}-1-piperidinecarboxylate

https://huagongshe.com/reaction/906349

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methoxyanilineHCID 581110—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant1,1-Dimethylethyl 4-{[4-fluoro-3-(methyloxy)phenyl]amino}-1-piperidinecarboxylateHCID 57699524—
Product1,1-Dimethylethyl 4-{[3-fluoro-4-(methyloxy)phenyl]amino}-1-piperidinecarboxylateHCID 57699519—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-oxo-1-piperidinecarboxylate and 3-fluoro-4-methoxyaniline using a method similar to that described for D9 in Description 9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012981B2
Source datasetuspto-grants-2011_09
ORD IDord-785565db9bb44f7a8ef61d89dd315045
Source noteuspto-grants-2011_09