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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906352Generated: October 25, 2026

2-Bromobenzonitrile → 1,1-Dimethylethyl 4-[(2-cyanophenyl)amino]-1-piperidinecarboxylate

https://huagongshe.com/reaction/906352

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromobenzonitrileHCID 16272—
Reactant4-Amino-1-Boc-piperidineHCID 1268291—
Reactant1,1-Dimethylethyl 4-[(3-cyanophenyl)amino]-1-piperidinecarboxylateHCID 25223796—
Product1,1-Dimethylethyl 4-[(2-cyanophenyl)amino]-1-piperidinecarboxylateHCID 57699512—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-amino-1-piperidinecarboxylate and 2-bromobenzonitrile using a method similar to that described for D5 in Description 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012981B2
Source datasetuspto-grants-2011_09
ORD IDord-993fdb532b8e4fcd81ba4f211bf7de53
Source noteuspto-grants-2011_09