Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906375Generated: October 30, 2026

4-Nitrobenzaldehyde → (3R,5S)-1-[(4-Nitrophenyl)methyl]-3,5-dimethylpiperazine

https://huagongshe.com/reaction/906375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-NitrobenzaldehydeHCID 541—
Reactantrel-(2R,6S)-2,6-dimethylpiperazineHCID 6950261—
Product(3R,5S)-1-[(4-Nitrophenyl)methyl]-3,5-dimethylpiperazineHCID 59262210—

Reaction Steps

The title compound was prepared from 4-nitrobenzaldehyde and (2R,6S)-2,6-dimethylpiperazine using a method similar to that described for D21 in Description 21A. MS (ES): MH+ 250.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012981B2
Source datasetuspto-grants-2011_09
ORD IDord-7416cc4c8b7d43bd90b8abc26600a64b
Source noteuspto-grants-2011_09