HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (2S)-2-methylpiperazine-1-carboxylate → tert-Butyl (2S)-4-{[6-bromo-1-oxo-2-(phenylsulfonyl)-1,2-dihydroisoquinolin-4-yl]methyl}-2-methylpiperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (2S)-2-methylpiperazine-1-carboxylate | HCID 10081508 | — |
| Reactant | 6-Bromo-4-(bromomethyl)-2-(phenylsulfonyl)isoquinolin-1(2H)-one | HCID 67130330 | — |
| Product | tert-Butyl (2S)-4-{[6-bromo-1-oxo-2-(phenylsulfonyl)-1,2-dihydroisoquinolin-4-yl]methyl}-2-methylpiperazine-1-carboxylate | HCID 67130295 | — |
Reaction Steps
The subtitle compound was prepared by the method of Example 11e using (S)-tert-butyl 2-methylpiperazine-1-carboxylate and 6-bromo-4-(bromomethyl)-2-(phenylsulfonyl)isoquinolin-1(2H)-one (Example 11d)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012980B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-60dd2a699c824abc8583d4e65a9affcb |
| Source note | uspto-grants-2011_09 |