N-Methylaniline → HCID 25104176, compound

HRID 906676Notes

Reaction equation

HRID 906676 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[N:9]1[O:10][N:11]=[C:12]2[CH:17]=[C:16]([C:18](Cl)=[O:19])[CH:15]=[CH:14][C:13]=12>>[CH3:1][N:2]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C:18]([C:16]1[CH:15]=[CH:14][C:13]2=[N:9][O:10][N:11]=[C:12]2[CH:17]=1)=[O:19]

Participants

3

Reactant 2

HCID 7515N-MethylanilineHCID 27354532,1,3-Benzoxadiazole-5-carbonyl chloride

Product 1

HCID 25104176HCID 25104176, compound

Procedure

Prepared from N-methylaniline and [2,1,3]-benzoxadiazole-5-carbonylchloride using the procedure described for Example 7. N-Methyl-N-phenyl-[2,1,3]-benzoxadiazole-5-carboxamide was isolated as a yellow oil. LC-MS, MH+=254; 1H NMR (300 MHz, CDCl3) δ 7.74 (s, 1H); 7.64 (d, 1H, J=9.6 Hz); 7.34 (d, 1H, J=9.6 Hz); 7.29-7.09 (m, 5H); 3.54 ppm (s, 3H).

Sources & evidence

ORD record
ord-b063774805164e32b93dfe9f2ec81304
Source dataset
uspto-grants-2011_09
Patent number
US08013003B2

Reaction notes

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