Sodium ion → N-[3-(6-chloro-7-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino}-1,3-benzodioxol-4-yl)prop-2-yn-1-yl]morpholine-4-carboxamide
Reaction equation
[CH3:47][Si:48]([N-:49][Si:50]([CH3:51])([CH3:52])[CH3:53])([CH3:54])[CH3:55].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[NH2:24][c:25]1[c:26]([Cl:46])[cH:27][c:28]([C:34]#[C:35][CH2:36][NH:37][C:38](=[O:39])[N:40]2[CH2:41][CH2:42][O:43][CH2:44][CH2:45]2)[c:29]2[c:30]1[O:31][CH2:32][O:33]2.[Na+:56].[O:57]=[CH:58][N:59]([CH3:60])[CH3:61]>>[c:2]1([NH:24][c:25]2[c:26]([Cl:46])[cH:27][c:28]([C:34]#[C:35][CH2:36][NH:37][C:38](=[O:39])[N:40]3[CH2:41][CH2:42][O:43][CH2:44][CH2:45]3)[c:29]3[c:30]2[O:31][CH2:32][O:33]3)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-66054820b4cc404697102248d7883a48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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