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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 907018Generated: October 30, 2026

Lithium Carbonate → HCID 59273071, compound

https://huagongshe.com/reaction/907018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium CarbonateHCID 11125—
Reactant2-Chloro-4-fluorobenzonitrileHCID 109000—
Reactant(2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-olHCID 59273011—
ProductHCID 59273071HCID 59273071—

Reaction Steps

By an operation in the same manner as in Example 1 and using (2S,3S)-2-ethyl-3-methylpyrrolidin-3-ol 0.5 oxalate (195 mg), 2-chloro-4-fluorobenzonitrile (320 mg) and lithium carbonate (200 mg), the title compound was obtained as a colorless solid (yield: 221.4 mg, yield: 75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08013008B2
Source datasetuspto-grants-2011_09
ORD IDord-b513727058674c0d97ea36b3dd41c63f
Source noteuspto-grants-2011_09