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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 907024Generated: November 1, 2026

Lithium Carbonate → HCID 59273030, compound

https://huagongshe.com/reaction/907024

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium CarbonateHCID 11125—
Reactant4-Fluoro-2-(trifluoromethyl)benzonitrileHCID 605085—
Reactant(2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-olHCID 59273011—
ProductHCID 59273030HCID 59273030—

Reaction Steps

By an operation in the same manner as in Example 1 and using (2S,3S)-2,3-diethylpyrrolidin-3-ol 0.5 oxalate (193 mg), 4-fluoro-2-(trifluoromethyl)benzonitrile (364 mg) and lithium carbonate (221 mg), the title compound was obtained as pale-yellow oil (yield: 219 mg, yield: 82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08013008B2
Source datasetuspto-grants-2011_09
ORD IDord-7803e5faaa8c42d2991b45012a4293b7
Source noteuspto-grants-2011_09