HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Carbonate → HCID 59273041, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Carbonate | HCID 11125 | — |
| Reactant | 4-Fluoro-2-methoxybenzonitrile | HCID 2783329 | — |
| Reactant | (2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-ol | HCID 59273011 | — |
| Product | HCID 59273041 | HCID 59273041 | — |
Reaction Steps
By an operation in the same manner as in Example 1 and using (2S,3R)-3-cyclopropyl-2-ethylpyrrolidin-3-ol 0.5 oxalate (185 mg), 4-fluoro-2-methoxybenzonitrile (290 mg) and lithium carbonate (198 mg), the title compound was obtained as a pale-yellow solid (yield: 144 mg, yield: 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013008B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-96622dad1a224252bb9041e34c1e0692 |
| Source note | uspto-grants-2011_09 |