HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Carbonate → HCID 67389475, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Carbonate | HCID 11125 | — |
| Reactant | 2,4-Difluoro-3-methylbenzonitrile | HCID 11344119 | — |
| Reactant | (2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-ol | HCID 59273011 | — |
| Product | HCID 67389475 | HCID 67389475 | — |
Reaction Steps
By an operation in the same manner as in Example 53 and using (2RS,3SR)-2,4,4-trimethylpyrrolidin-3-ol 0.5 oxalate (214 mg), 2,4-difluoro-3-methylbenzonitrile (240 mg) and lithium carbonate (246 mg), the title compound was obtained as a colorless solid (yield: 112 mg, yield: 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013008B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-7b8cb2d6715e4b8fbe74037aee664b11 |
| Source note | uspto-grants-2011_09 |