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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 907271Generated: November 1, 2026

Methylamine → N-Cyclopropyl-4-methyl-3-(2-(4-(2-(methylamino)ethoxy)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)benzamide

https://huagongshe.com/reaction/907271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant3-(2-(4-(2-Chloroethoxy)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-N-cyclopropyl-4-methylbenzamideHCID 57551830—
ProductN-Cyclopropyl-4-methyl-3-(2-(4-(2-(methylamino)ethoxy)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)benzamideHCID 57551794—

Reaction Steps

The title compound was prepared according to the method of Example 32 step (iii) using the product of Example 32 step (ii) and methylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012979B2
Source datasetuspto-grants-2011_09
ORD IDord-6164e54ed82d43f894557949fc43a586
Source noteuspto-grants-2011_09