反应详情

A mixture of the product of Example 37 step ii) (5 g) and benzylamine (3 mL) in methanol (20 mL) was heated at reflux for 40 hours. The reaction was concentrated to half volume, then treated with acetonitrile. The sub-title compound was collected by filtration, washing with acetonitrile (5.30 g).

1. temperaturewas heated
2. temperatureat reflux for 40 hours
3. concentrationThe reaction was concentrated to half volume
4. additiontreated with acetonitrile
5. filtrationThe sub-title compound was collected by filtration
6. washwashing with acetonitrile (5.30 g)