1-Methylpiperazine → N-Cyclopropyl-3-fluoro-4-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)-2-(4-(methylsulfonyl)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)benzamide

Participants

Role	Name	HCID	Charge
Reactant	1-Methylpiperazine	HCID 53167	—
Reactant	N-Cyclopropyl-3-fluoro-5-(4-formyl-2-(4-(methylsulfonyl)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylbenzamide	HCID 57551746	—
Product	N-Cyclopropyl-3-fluoro-4-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)-2-(4-(methylsulfonyl)benzyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)benzamide	HCID 57551753	—

The title compound was prepared by the method of Example 59 step iv) using product of example 112 step i) and 1-methyl-piperazine.