(1,4-Dibenzyl-1,4-diazepan-5-yl)methanol → HCID 23090220, compound

Participants

Reaction Steps

To a solution of (1,4-dibenzyl-1,4-diazepan-5-yl)methanol (500 mg) (prepared as described in Chin. Chem. Lett., 2001, 12, 951) in methanol (10 mL) was added 5% wt. palladium on charcoal (171 mg) and the mixture stirred under a 5 bar hydrogen atmosphere for 16 hours. The reaction mixture was filtered through celite and the liquors concentrated to dryness to give the sub-title compound (210 mg) as a colourless oil.

Provenance & Evidence