HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → HCID 4349058, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl 4-methoxyphenylacetate | HCID 90266 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 4349058 | HCID 4349058 | — |
Reaction Steps
Using the procedure for Example 22, (4-methoxy-phenyl)-acetic acid methyl ester Compound 22a was reacted with ethylamine and sodium hydride in DMSO at room temperature to provide N-ethyl-2-(4-methoxy-phenyl)-acetamide Compound 24a. Compound 24a was reacted with borotribromide in dichloromethane to yield N-ethyl-2-(4-hydroxy-phenyl)-acetamide Compound 24b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013153B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-c461237bf6e1408885153fa78ef85f67 |
| Source note | uspto-grants-2011_09 |