反应详情

温度

145 °C

To a stirred suspension of Step 2 product (1 eq) in acetic anhydride (2.5 v/w) under nitrogen was added potassium acetate (0.02 eq). The reaction mixture was heated to, and stirred at the reflux temperature (145° C.) for 2 hours. The resultant solution was concentrated in vacuo, and purged with toluene to afford a brown oil.

1. temperatureThe reaction mixture was heated to, and
2. concentrationThe resultant solution was concentrated in vacuo
3. custompurged with toluene
4. customto afford a brown oil