反应详情

A cold solution of H2SO4 (2.9 mL) in MeOH (28.96 mL) was added to 1-methyl-4-nitropyrrole-2-carboxylic acid (2.897 g, 2.35 mmol). The mixture was refluxed for 24 hr. Water was added and the mixture extracted CHCl3. The organic layer was dried (MgSO4), and the solvent evaporated under vacuum to afford the creamy white product. NMR as previously reported.

1. temperatureThe mixture was refluxed for 24 hr
2. extractionthe mixture extracted CHCl3
3. dry with materialThe organic layer was dried (MgSO4)
4. customthe solvent evaporated under vacuum
5. customto afford the creamy white product