Methylamine → N-Methyl-4-(2-oxopropyl)benzene-1-sulfonamide

HRID 908145Notes

Reaction equation

HRID 908145 reaction equation
[O:1]=[C:2]([CH3:14])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[CH:6][CH:5]=1.[CH3:15]N>>[CH3:15][NH:13][S:10]([C:7]1[CH:6]=[CH:5][C:4]([CH2:3][C:2](=[O:1])[CH3:14])=[CH:9][CH:8]=1)(=[O:11])=[O:12]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 215301384-(2-Oxopropyl)benzene-1-sulfonamide

Product 1

HCID 58436479N-Methyl-4-(2-oxopropyl)benzene-1-sulfonamide

Procedure

4-(2-Oxo-propyl)-benzenesulfonyl chloride (prepared as described in European patent specification EP 91749 A2) (0.087 g, 4.1 mmol) was treated with methylamine to give the title compound.

Sources & evidence

ORD record
ord-15711718751c49ea9674f2074f50db9a
Source dataset
uspto-grants-2011_09
Patent number
US08017608B2

Reaction notes

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