HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenylacetone → 1-(4-Amino-3-chlorophenyl)propan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenylacetone | HCID 11788379 | — |
| Reactant | N-chlorosuccinamide | HCID 15238416 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(4-Amino-3-chlorophenyl)propan-2-one | HCID 58012485 | — |
Reaction Steps
N-Chlorosuccinamide (1.79 g, 13.4 mmol) is added to a stirred solution of 1-(4-amino-phenyl)-propan-2-one (2.0 g, 13.4 mmol) in chloroform at 0° C. After 1 hour the reaction is complete. The solvent is removed to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017608B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-679a2e7e43a647429ca8cccd7dd4b52e |
| Source note | uspto-grants-2011_09 |