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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 908156Generated: October 31, 2026

1-(4-Amino-3-chlorophenyl)propan-2-one → 4-(2-Chloro-4-methyl-thiazol-5-yl)-benzenesulfonamide

https://huagongshe.com/reaction/908156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Amino-3-chlorophenyl)propan-2-oneHCID 58012485—
Reactant2-Chloro-4-(2-oxo-propyl)-benzenesulfonamideHCID 67391757—
Reactant4-(2-Chloro-4-methyl-thiazol-5-yl)-phenylamineHCID 67391768—
Product4-(2-Chloro-4-methyl-thiazol-5-yl)-benzenesulfonamideHCID 67392041—

Reaction Steps

Starting from 4-(2-chloro-4-methyl-thiazol-5-yl)-phenylamine (25c) and following the two step process described for the preparation of 2-chloro-4-(2-oxo-propyl)-benzenesulfonamide (Example 23c) from 1-(4-amino-3-chloro-phenyl)-propan-2-one (Example 23a) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08017608B2
Source datasetuspto-grants-2011_09
ORD IDord-2ed7c4af63cc429aa319e6d97dcfbf5d
Source noteuspto-grants-2011_09