HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 4-{4-Methyl-2-[5-(2-morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamino]-thiazol-5-yl}-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-(2-Oxopropyl)benzene-1-sulfonamide | HCID 21530138 | — |
| Reactant | HCID 86761402 | HCID 86761402 | — |
| Product | 4-{4-Methyl-2-[5-(2-morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamino]-thiazol-5-yl}-benzenesulfonamide | HCID 86761403 | — |
Reaction Steps
The titled compound is prepared from 4-(2-oxo-propyl)-benzenesulfonyl chloride (prepared as described in European patent specification EP 91749 A2) following the procedures described in Example 1, using ammonia and [5-(2-morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-yl}-thiourea (54c).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017608B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-58a7355d0dba4a35be6ec81a90f074f0 |
| Source note | uspto-grants-2011_09 |