Hydrochloric Acid → HCID 178510551, compound

Participants

Reaction Steps

tert-butyl[(6-{[(2,2,2-trifluoroethyl)amino]carbonyl}-3H-imidazo[4,5-b]pyridin-2-yl)methyl]carbamate (0.657 g, 1.76 mmol) was treated with 4N HCl in dioxane (30 ml). The reaction mixture was stirred at room temperature overnight, concentrated under reduced pressure and co-evaporated with EtOAc twice to give title compound. This crude product was used in the next step without further purification.

Provenance & Evidence