HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 59463765, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59463762 | HCID 59463762 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59463765 | HCID 59463765 | 65% |
Reaction Steps
TFA (2 ml) was added to a solution of compound 42 (100 mg, 0.18 mmol) in dichloromethane (4 ml) and the solution was stirred at room temperature. After 30 min the solvents were evaporated in vacuo and the afforded residue was purified by column chromatography on silica gel which gave the title compound (52 mg, 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017620B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-6614962b560742cbb904a1d95279d8ee |
| Source note | uspto-grants-2011_09 |