反应详情

温度

80 °C

A mixture of the compound (250 mg) obtained in Example 4 and 2-bromo-3-oxobutyric acid tert-butyl ester (168 mg) in acetonitrile (1.25 ml) was stirred at 80° C. for 20 min. The reaction mixture was concentrated under reduced pressure, and the residue was purified by thin layer chromatography (ethyl acetate:n-hexane=2:3) to give the title compound (268 mg).

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customthe residue was purified by thin layer chromatography (ethyl acetate:n-hexane=2:3)