反应详情

A solution of the compound (224 mg) obtained in Example 5 in trifluoroacetic acid (1.1 ml) was stirred at room temperature for 1 hr. The reaction mixture was concentrated under reduced pressure, toluene was added to the residue, and the mixture was concentrated again under reduced pressure. Diisopropyl ether was added to the residue, and the mixture was stirred at room temperature. The precipitated crystals were collected by filtration, and dried to give the title compound (97 mg).

1. concentrationThe reaction mixture was concentrated under reduced pressure, toluene
2. additionwas added to the residue
3. concentrationthe mixture was concentrated again under reduced pressure
4. additionDiisopropyl ether was added to the residue
5. filtrationThe precipitated crystals were collected by filtration
6. customdried