反应详情

To a solution of the compound (2.03 g) obtained in Step 1 in tetrahydrofuran (40 ml) was added dropwise, with stirring under ice-cooling, 1.0M tetrabutylammonium fluoride tetrahydrofuran solution (7.38 ml). After stirring at room temperature for 1 hr, the reaction mixture was concentrated under reduced pressure. The concentrated residue was purified by silica gel column chromatography (ethyl acetate:methanol=9:1) to give the title compound (1.06 g).

1. temperaturecooling
2. stirringAfter stirring at room temperature for 1 hr
3. concentrationthe reaction mixture was concentrated under reduced pressure
4. customThe concentrated residue was purified by silica gel column chromatography (ethyl acetate:methanol=9:1)